Visual Tracking and Servoing System for Experiment of Optogenetic Control of Brain Activity

To study the wireless optogenetic control of neural activity using fully implantable devices, we designed experiments that we make laser emit 980-nm light on the experiment mice brain where the upconversion nanoparticles which works as transducer to convert near-infrared energy to visible lights is implanted, observe the mice activity and record its trajectories. Hence, we propose and implement a automatic visual tracking and servoing system to aid and speed up the experiment. Usually, people drives PTZ for active surveillance tracking which aims to keep the object in the middle of the field of view. In this work, we utilize a PTZ to cast laser beam on the target object as the actuator (PTZ) and the sensor (camera) decoupled that they can be arbitrarily installed. And we also present the automatic parameters calibration method and mathematical modeling for this system to keep high accuracy.